novel replacements for the JWH and AM series
AKB48 or N-adamantyl-1-pentylindazole-3-carboxamide is a designer drug that acts as a potent cannabinoid receptor full agonist at both the CB1 and CB2 receptors. It has been found as an ingredient in synthetic cannabis smoking blends. It is unclear who AKB48 was originally developed by, but its name would suggest that it is Japanese in origin. No information has yet been published on its receptor binding or pharmacological profile, but it is structurally related to compounds such as AM-1248, 2NE1, STS-135, and AB-001, which are known to be potent cannabinoid agonists.